diff --git a/Docs/Whats_New.md b/Docs/Whats_New.md
index e9b43973..3c698a62 100644
--- a/Docs/Whats_New.md
+++ b/Docs/Whats_New.md
@@ -33,6 +33,9 @@ Released TBD
   disable recent fixes to handling LOD for arrayed depth images in shaders, 
   on Apple Silicon, when those fixes cause regression in rendering behavior.
 - Identify each unsupported device feature flag that the app attempts to be enable.
+- Populate `deviceUUID` from `MTLDevice` location and peer group info, 
+  which should be unique, and constant across OS reboots.
+- Populate `deviceLUID` from `MTLDevice.registryID`. 
 - For correctness, set `VkPhysicalDeviceLimits::lineWidthGranularity` to `1`.
 - Improve GitHub CI production of binary artifacts on submission and release.
 
diff --git a/MoltenVK/MoltenVK/GPUObjects/MVKDevice.h b/MoltenVK/MoltenVK/GPUObjects/MVKDevice.h
index e1f7e310..037d7017 100644
--- a/MoltenVK/MoltenVK/GPUObjects/MVKDevice.h
+++ b/MoltenVK/MoltenVK/GPUObjects/MVKDevice.h
@@ -1064,6 +1064,14 @@ protected:
 /** Returns the registry ID of the specified device, or zero if the device does not have a registry ID. */
 uint64_t mvkGetRegistryID(id<MTLDevice> mtlDevice);
 
+/**
+ * Returns a value identifying the physical location of the specified device.
+ * The returned value is a hash of the location, locationNumber, peerGroupID,
+ * and peerIndex properties of the device. On devices with only one built-in GPU,
+ * the returned value will be zero.
+ */
+uint64_t mvkGetLocationID(id<MTLDevice> mtlDevice);
+
 /** Returns whether the MTLDevice supports BC texture compression. */
 bool mvkSupportsBCTextureCompression(id<MTLDevice> mtlDevice);
 
diff --git a/MoltenVK/MoltenVK/GPUObjects/MVKDevice.mm b/MoltenVK/MoltenVK/GPUObjects/MVKDevice.mm
index ba0c3310..6adabc31 100644
--- a/MoltenVK/MoltenVK/GPUObjects/MVKDevice.mm
+++ b/MoltenVK/MoltenVK/GPUObjects/MVKDevice.mm
@@ -727,15 +727,21 @@ void MVKPhysicalDevice::getProperties(VkPhysicalDeviceProperties2* properties) {
 	}
 }
 
+// Since these are uint8_t arrays, use Big-Endian byte ordering,
+// so a hex dump of the array is human readable in its parts.
 void MVKPhysicalDevice::populateDeviceIDProperties(VkPhysicalDeviceVulkan11Properties* pVk11Props) {
 	uint8_t* uuid;
 	size_t uuidComponentOffset;
 
-	//  ---- Device ID ----------------------------------------------
+	//  ---- Device UUID ----------------------------------------------
 	uuid = pVk11Props->deviceUUID;
 	uuidComponentOffset = 0;
 	mvkClear(uuid, VK_UUID_SIZE);
 
+	// From Vulkan spec: deviceUUID must be universally unique for the device,
+	// AND must be immutable for a given device across instances, processes,
+	// driver APIs, driver versions, and system reboots.
+
 	// First 4 bytes contains GPU vendor ID
 	uint32_t vendorID = _properties.vendorID;
 	*(uint32_t*)&uuid[uuidComponentOffset] = NSSwapHostIntToBig(vendorID);
@@ -746,10 +752,10 @@ void MVKPhysicalDevice::populateDeviceIDProperties(VkPhysicalDeviceVulkan11Prope
 	*(uint32_t*)&uuid[uuidComponentOffset] = NSSwapHostIntToBig(deviceID);
 	uuidComponentOffset += sizeof(deviceID);
 
-	// Last 8 bytes contain the GPU registry ID
-	uint64_t regID = mvkGetRegistryID(_mtlDevice);
-	*(uint64_t*)&uuid[uuidComponentOffset] = NSSwapHostLongLongToBig(regID);
-	uuidComponentOffset += sizeof(regID);
+	// Last 8 bytes contain the GPU location identifier
+	uint64_t locID = mvkGetLocationID(_mtlDevice);
+	*(uint64_t*)&uuid[uuidComponentOffset] = NSSwapHostLongLongToBig(locID);
+	uuidComponentOffset += sizeof(locID);
 
 	// ---- Driver ID ----------------------------------------------
 	uuid = pVk11Props->driverUUID;
@@ -772,10 +778,10 @@ void MVKPhysicalDevice::populateDeviceIDProperties(VkPhysicalDeviceVulkan11Prope
 	*(uint32_t*)&uuid[uuidComponentOffset] = NSSwapHostIntToBig(gpuCap);
 	uuidComponentOffset += sizeof(gpuCap);
 
-	// ---- LUID ignored for Metal devices ------------------------
-	mvkClear(pVk11Props->deviceLUID, VK_LUID_SIZE);
-	pVk11Props->deviceNodeMask = 0;
-	pVk11Props->deviceLUIDValid = VK_FALSE;
+	// ---- Device LUID ------------------------
+	*(uint64_t*)pVk11Props->deviceLUID = NSSwapHostLongLongToBig(mvkGetRegistryID(_mtlDevice));
+	pVk11Props->deviceNodeMask = 1;		// Per Vulkan spec
+	pVk11Props->deviceLUIDValid = VK_TRUE;
 }
 
 void MVKPhysicalDevice::populateSubgroupProperties(VkPhysicalDeviceVulkan11Properties* pVk11Props) {
@@ -2732,6 +2738,8 @@ void MVKPhysicalDevice::initGPUInfoProperties() {
 }
 #endif	//MVK_IOS_OR_TVOS
 
+// Since this is a uint8_t array, use Big-Endian byte ordering,
+// so a hex dump of the array is human readable in its parts.
 void MVKPhysicalDevice::initPipelineCacheUUID() {
 
 	// Clear the UUID
@@ -4835,6 +4843,32 @@ uint64_t mvkGetRegistryID(id<MTLDevice> mtlDevice) {
 	return [mtlDevice respondsToSelector: @selector(registryID)] ? mtlDevice.registryID : 0;
 }
 
+uint64_t mvkGetLocationID(id<MTLDevice> mtlDevice) {
+	uint64_t hash = 0;
+
+#if MVK_MACOS && !MVK_MACCAT
+	// All of these device properties were added at the same time,
+	// so only need to check for the presence of one of them.
+	if ([mtlDevice respondsToSelector: @selector(location)]) {
+		uint64_t val;
+
+		val = mtlDevice.location;
+		hash = mvkHash(&val, 1, hash);
+
+		val = mtlDevice.locationNumber;
+		hash = mvkHash(&val, 1, hash);
+
+		val = mtlDevice.peerGroupID;
+		hash = mvkHash(&val, 1, hash);
+
+		val = mtlDevice.peerIndex;
+		hash = mvkHash(&val, 1, hash);
+	}
+#endif
+
+	return hash;
+}
+
 // If the supportsBCTextureCompression query is available, use it.
 // Otherwise only macOS supports BC compression.
 bool mvkSupportsBCTextureCompression(id<MTLDevice> mtlDevice) {